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Anticoagulants: Phenobarbital lowers the plasma levels of dicumarol (name previously made use of: bishydroxycoumarin) and causes a lessen in anticoagulant action as calculated with the prothrombin time. Barbiturates can induce hepatic microsomal enzymes resulting in increased metabolism and lessened anticoagulant reaction of oral anticoagulants (e.
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